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In several studies, we have examined the reliability and validity of SWAP prototype diagnosis using both the DSM prototypes (composite descriptions of patients with a DSM-defined PD) and the empirically derived prototypes Both approaches have demonstrated substantial validity and reliability For example, interrater reliability for both sets of diagnoses averages > 80 (Pearson s correlation); SWAP PD scores obtained by interview correlate > 80 with PD scores obtained from the treating clinician s description of the patient using the SWAP ( blind to interview results); and borderline and antisocial diagnosis made using the SWAP correlate in predicted ways with borderline and antisocial scales from well-validated self-report instruments (Bradley et al, 2003; Westen & Muderrisoglu, 2003).

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The _x, _y, _rotation, _xscale, _yscale, _height, _width, _alpha, and _visible properties are affected by transformations on the movie clip s parent, and transform the movie clip and any of the clip s children. The _focusrect, _highquality, _quality, and _soundbuftime properties are global; they belong only to the level 0 main Timeline. All other properties belong to each movie clip or loaded level. For a list of movie clip properties, see the MovieClip entry in the online ActionScript Dictionary in the Help menu.

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We have recently completed our first test of the simple prototype rating system described earlier as an alternative in clinical practice to the DSM count /cutoff approach, focusing on the four Cluster B disorders (antisocial, borderline, histrionic, and narcissistic; Westen, Shedler, & Bradley, 2004) We chose the Cluster B disorders because they are the most studied, have the best-known correlates, and show high comorbidity A random national sample of experienced psychiatrists and clinical psychologists (N = 291) described a randomly selected patient in their care Clinicians completed an Axis II checklist, which provided present /absent data on each of the DSM-IV PDs, which we used to generate both categorical DSM-IV diagnoses (using DSM-IV decision rules) and dimensional diagnoses (number of symptoms met for each disorder) Half of the clinicians then diagnosed their patients using prototypes of the DSM-IV PDs ( hereafter, DSM prototypes).

in unconnected calci ed and unorganized bone clusters [Meinel et al, 2004b] The biodegradation of collagen type I can be adapted through cross-linkage of the molecules, thereby matching the requirements for bone implants However, the tissue reaction to cross-linked collagen scaffolds was quite unpredictable and resulted in spontaneous calci cation, cytotoxic effects, and scar formation around the implant [van Luyn et al, 1992] Spontaneous calci cation might in particular result in problems for the engineering of osteochondral plugs, when the formation of pure cartilaginous tissue is impaired by the uncontrolled, and not cell-mediated, mineralization These remarkable differences in cytotoxicity were connected to residual agents as a consequence of processing and the cross-linking agents used [van Luyn et al, 1992, van Wachem et al, 2001].

adaptive and constructive Accepting rather than overturning a hospitable reality seems a sound course; or as it is said, If it ain t broke, don t x it Often re ective and deliberate, those who are passively oriented manifest few overt strategies to gain their ends They display a seeming inertness, a phlegmatic lack of ambition or persistence, a tendency toward acquiescence, a restrained attitude in which they initiate little to modify events, waiting for the circumstances of their environment to take their course before making accommodations Some persons may be temperamentally ill-equipped to rouse or assert themselves; perhaps past experience has deprived them of opportunities to acquire a range of competencies or con dence in their ability to master the events of their environment; equally possible is a naive con dence that things will come their way with little or no effort on their part.

The other half diagnosed their patients using prototypes derived empirically using Qfactor analysis ( hereafter, empirical prototypes) Clinicians then completed a number of ratings comparing the DSM diagnostic method with the prototype approach they had used on several measures of clinical efficiency and utility We compared the two prototype systems (DSM and empirical) to the count /cutoff approach on three sets of criteria used to test the adequacy of a diagnostic system: diagnostic redundancy (comorbidity), validity (in this case, ability to predict ratings of adaptive functioning, treatment response, and variables relevant to etiology), and clinical utility (clinicians ratings of ease of use, comprehensiveness, informational value, and utility in communicating with other clinicians).

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